A comprehensive forced degradation studies of Cariprazine hydrochloride using LC-HRMS/MS and in silico toxicity predictions of its degradation products
| dc.contributor.author | Jain, Mohit | |
| dc.contributor.author | Khan, Shahnawaz | |
| dc.date.accessioned | 2023-09-21T16:04:43Z | |
| dc.date.available | 2023-09-21T16:04:43Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Cariprazine hydrochloride is a second-generation antipsychotic drug and has been approved by the US Food and Drug Administration and the European Medicines Agency. Herein, we have reported a stability-indicating assay method for the Cariprazine hydrochloride and characterization of its major degradation products using LCHRMS/ MS. The drug substance Cariprazine hydrochloride was subjected to acid, base, oxidation, thermal and photolytic stress degradation. | en_US |
| dc.identifier.citation | Mohit Jain, Shahnawaz Khan A comprehensive forced degradation studies of Cariprazine hydrochloride using LC-HRMS/MS and in silico toxicity predictions of its degradation products | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/5970 | |
| dc.language.iso | en | en_US |
| dc.publisher | Journal of Pharmaceutical and Biomedical Analysis | en_US |
| dc.subject | Pharmaceutical and Biomedical Analysis | en_US |
| dc.title | A comprehensive forced degradation studies of Cariprazine hydrochloride using LC-HRMS/MS and in silico toxicity predictions of its degradation products | en_US |
| dc.type | Article | en_US |